Fluoxetine how much should i take

Accumulation and slow elimination – the relatively slow elimination of fluoxetine elimination half-life of 1 to 3 days after acute administration and 4 to 6 days after chronic administration and its active metabolite, norfluoxetine elimination half-life of 4 to 16 days after acute and chronic administration , leads to significant accumulation of these active species in chronic use and delayed attainment of steady state, even when a fixed dose is used.